The transportation of hazardous goods both locally and internationally are subject to various regulations depending on the origin and destination country.. The entities undertaking the transportation of dangerous goods must strictly adhere to these regulations..

For intermodal transport, these rules and regulations may be related to transport within a political or economic union or trading zone etc..

Most of these regulations maybe based on the United Nations Recommendations on Transport of Dangerous Goods (the Orange book)..

However, international rules like the ADR and national rules like the CFR49 may differ from the United Nations Recommendations on the Transport of Dangerous Goods..